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Rabbit Anti-ZA20D3 antibody
ZA20D3 is a zinc-finger protein located on chromosome 15. It is associated with PRK1.
Function:
Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes
Subunit:
Interacts with PKN1 (By similarity). Interacts with TRAF2. Interacts with mono- and polyubiquitin. Interacts with PEX6. Interacts with PEX5 (Cys-linked ubiquitinated) (By similarity).
Subcellular Location:
Cytoplasm
Tissue Specificity:
Widely expressed with high level in heart, skeletal muscle, liver, kidney and placenta.
Similarity:
Contains 1 A20-type zinc finger.
Contains 1 AN1-type zinc finger.
SWISS:
Q6FIF0
Gene ID:
54469
Database links:
Entrez Gene: 54469 Human
Entrez Gene: 65098 Mouse
Entrez Gene: 293067 Rat
Omim: 610183 Human
SwissProt: Q6FIF0 Human
SwissProt: Q9BQF7 Human
SwissProt: Q9DCH6 Mouse
SwissProt: Q6DGF4 Rat
Unigene: 306329 Human
Unigene: 209349 Mouse
Unigene: 130357 Rat
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