The BTB is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. ZBTB3 (zinc finger and BTB domain containing 3) is a 574 amino acid protein that contains one BTB (POZ) domain and two C2H2-type zinc fingers. Localized to the nucleus, ZBTB3 is thought to play a role in transcriptional regulation events. The gene encoding ZBTB3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
Function:
May be involved in transcriptional regulation.
Subcellular Location:
Nucleus.
Similarity:
Contains 1 BTB (POZ) domain.
Contains 2 C2H2-type zinc fingers.
SWISS:
Q9H5J0
Gene ID:
79842
Database links:
Entrez Gene: 79842 Human
Entrez Gene: 75291 Mouse
Entrez Gene: 499313 Rat
SwissProt: Q9H5J0 Human
SwissProt: Q91X45 Mouse
Unigene: 147554 Human
Unigene: 23423 Mouse
|
|