Rabbit Anti-C9orf89 antibody

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Bcl10 interacting protein with CARD protein; BinCARD; Chromosome 9 open reading frame 89; BINCA_HUMAN.

Cat:

SL15346R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human C9orf89:1-100/228

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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C9orf89 plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. It may inhibit the phosphorylation of BCL10 in a CARD-dependent manner. There are two isoforms.

Function:
Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.

Subunit:
Associates with BCL10 by CARD-CARD interaction.

Subcellular Location:
Nucleus. Note=Co-expression with BCL10 induced translocation from nucleus to cytosol.

Tissue Specificity:
Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.

Post-translational modifications:
Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 1 CARD domain.

SWISS:
Q96LW7

Gene ID:
84270

Database links:

Entrez Gene: 84270 Human

SwissProt: Q96LW7 Human

Unigene: 434213 Human

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