Rabbit Anti-HECTD3 antibody

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HECT; HECT domain containing protein 3; Probable E3 ubiquitin protein ligase HECTD3; HECD3_HUMAN.

Cat:

SL15448R

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human HECTD3:301-400/961

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity).

Subunit:
Interacts with TRIOBP. Interacts with STX8 (By similarity).

Subcellular Location:
Cytoplasm, perinuclear region (By similarity).

Similarity:
Contains 1 DOC domain.
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.

SWISS:
Q5T447

Gene ID:
79654

Database links:

Entrez Gene: 79654 Human

SwissProt: Q5T447 Human

Unigene: 525084 Human

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