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Rabbit Anti-ZNF323 antibody
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the Krüppel C2H2-type zinc-finger protein family, ZNF323 (zinc finger protein 323) is a 406 amino acid protein containing six C2H2-type zinc fingers and one SCAN box domain. Specifically, C2H2-type zinc fingers function to bind DNA, while SCAN box domains are thought to participate in protein-protein interactions. Therefore, it is probable that ZNF323 functions as a transcription factor. With highest expression in kidney, liver and lung and weaker expression in brain, heart, intestine, muscle, cholecyst and pancreas, ZNF323 is localized to the nucleus. It is also suggested that ZNF323 may play a role in the development of multiple embryonic organs.
Function:
May function as a transcription factor. May be involved in the development of multiple embryonic organs.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed at high levels in the lung, liver, and kidney, while weakly expressed in intestine, brain, muscle, cholecyst, heart, and pancreas.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 6 C2H2-type zinc fingers.
Contains 1 SCAN box domain.
SWISS:
Q96LW9
Gene ID:
64288
Database links:
Entrez Gene: 64288 Human
Omim: 610794 Human
SwissProt: Q96LW9 Human
Unigene: 656413 Human
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