Home > Product > Antibody > Rabbit Anti-IQGAP2 antibody
IQGA2_HUMAN; Iqgap2; Ras GTPase activating-like protein; Ras GTPase-activating-like protein IQGAP2.
Cat:
SL7176R
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human IQGAP2:51-150/1575
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008]

Function:
Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.

Tissue Specificity:
Isoform 2 expression is enhanced in testis.

Similarity:
Contains 1 CH (calponin-homology) domain.
Contains 3 IQ domains.
Contains 1 Ras-GAP domain.
Contains 1 WW domain.

SWISS:
Q13576

Gene ID:
10788

Database links:

Entrez Gene: 10788 Human

Entrez Gene: 544963 Mouse

Omim: 605401 Human

SwissProt: Q13576 Human

SwissProt: Q3UQ44 Mouse

Unigene: 291030 Human

Unigene: 38878 Mouse


Unigene: 38878 Mouse

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