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Home > Product > Antibody > Rabbit Anti-Calcitonin receptor antibody
Calcitonin receptor precursor; Calcr; CRT; CT R; CTR; CTR1; CALCR_HUMAN; CT-R.
Cat:
SL10516R
Species Reactivity：
(predicted: Human,)
Immunogen：
KLH conjugated synthetic peptide derived from human Calcitonin receptor:1-100/490<Extracellular>
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
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Product PDFs
Datasheet:


This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

Function:
This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.

Subunit:
Interacts with GPRASP2.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 2 family.

SWISS:
P30988

Gene ID:
799

Database links:

Entrez Gene: 799 Human

Omim: 114131 Human

SwissProt: P30988 Human

Unigene: 489127 Human



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