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Rabbit Anti-C19orf42 antibody
C19orf42 (chromosome 19 open reading frame 42) is a 75 amino acid single-pass type I membrane protein that is encoded by a gene located on human chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.
Subcellular Location:
Membrane.
Similarity:
Belongs to the UPF0608 family.
SWISS:
Q9BQ49
Gene ID:
79086
Database links:
Entrez Gene: 79086 Human
SwissProt: Q9BQ49 Human
Unigene: 356467 Human
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