This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Tissue Specificity:
Highly concentrated in brain, lung and intestinal mucosa.
Similarity:
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.
Contains 1 AGSLCkinase SLCterminal domain.
Contains 2 cyclic nucleotide-binding domains.
Contains 1 protein kinase domain.
SWISS:
Q13237
Gene ID:
5593
Database links:
Entrez Gene: 5593 Human
Entrez Gene: 19092 Mouse
Entrez Gene: 25523 Rat
Omim: 601591 Human
SwissProt: Q13237 Human
SwissProt: Q61410 Mouse
SwissProt: Q64595 Rat
Unigene: 570833 Human
Unigene: 263002 Mouse
Unigene: 87721 Rat
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