Rabbit Anti-CHCHD3 antibody

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CHCH3_HUMAN; CHCHD 3; Chchd3; Coiled coil helix coiled coil helix domain containing 3; Coiled coil helix coiled coil helix domain containing protein 3 mitochondrial; Coiled-coil-helix-coiled-coil-helix domain-containing protein 3; FLJ20420; mitocho

Cat:

SL13887R

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human CHCHD3:1-100/227

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Required for maintenance of mitochondrial crista integrity and mitochondrial function. May act as a scaffolding protein that stabilizes protein complexes involved in crista architecture and protein import. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription.

Subcellular Location:
Mitochondrion inner membrane. Cytoplasm. Nucleus.

Tissue Specificity:
Detected at low levels in brain, placenta, lung, liver, kidney and pancreas with increased levels in heart and skeletal muscle. Higher expression in primary lung cancers than in normal lung tissue.

Similarity:
Contains 1 CHCH domain.

SWISS:
Q9NX63

Gene ID:
54927

Database links:

Entrez Gene: 54927 Human

Entrez Gene: 616477 Cow

Entrez Gene: 66075 Mouse

Omim: 613748 Human

SwissProt: Q5E9D3 Cow

SwissProt: Q9NX63 Human

SwissProt: Q9CRB9 Mouse

Unigene: 655010 Human

Unigene: 21501 Mouse

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