Home > Product > Antibody > Rabbit Anti-CHES1 antibody
C14orf116; Checkpoint suppressor 1; Forkhead box protein N3; Foxn3; FOXN3_HUMAN; FXN3; FXN3; PRO1635.
Cat:
SL13899R
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human CHES1:401-490/490
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]

Function:
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).

Subcellular Location:
Nucleus.

Similarity:
Contains 1 fork-head DNA-binding domain.

SWISS:
O00409

Gene ID:
1112

Database links:

Entrez Gene: 1112 Human

Entrez Gene: 71375 Mouse

Entrez Gene: 314374 Rat

Omim: 602628 Human

SwissProt: O00409 Human

SwissProt: Q499D0 Mouse

Unigene: 434286 Human

Unigene: 621371 Human

Unigene: 341972 Mouse

Unigene: 392143 Mouse

Unigene: 448530 Mouse



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