Rabbit Anti-Connexin 30.3 antibody

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GJB4; Connexin 30.3; Cx30.3; CXB4_HUMAN; Gap junction beta 4 protein.

Cat:

SL13971R

Species Reactivity：

(predicted: Human,Mouse,Rat,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human Connexin 30.3:121-220/266

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a transmembrane connexin protein that is a component of gap junctions. Mutations in this gene have been associated with erythrokeratodermia variabilis, progressive symmetric erythrokeratoderma and hearing impairment. [provided by RefSeq, Dec 2009]

Function:
Connexins are homologous four transmembrane domain proteins and major components of gap junctions. The GJB4 gene encodes connexin 30.3 (Cx30.3). A mutation in connexin 30.3 is causally involved in erythrokeratodermia variabilis (EKV), a mostly autosomal dominant disorder of keratinization.

Subcellular Location:
Plasma membrane

SWISS:
Q9NTQ9

Gene ID:
127534

Database links:

Entrez Gene: 127534 Human

Entrez Gene: 14621 Mouse

Omim: 605425 Human

SwissProt: Q9NTQ9 Human

SwissProt: Q02738 Mouse

Unigene: 351203 Human

Unigene: 56906 Mouse

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