Home > Product > Antibody > Rabbit Anti-DBNDD2/CK1BP antibody
C20orf35; Casein kinase-1 binding protein; CK1BP; DBND2_HUMAN; Dbndd2; Dysbindin (dystrobrevin binding protein 1) domain containing 2; Dysbindin domain-containing protein 2; HSMNP1; SCF apoptosis response protein 1.
Cat:
SL14203R
Species Reactivity:
(predicted: Human,)
Immunogen:
KLH conjugated synthetic peptide derived from human DBNDD2/CK1BP:151-259/259
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


CK1BP is a 261 amino acid member of the dysbindin family and is a paralog of dysbindin, a protein trafficking protein involved in lysosome biosynthesis that has been associated with schizophrenia and muscular dystrophy. Human and rat HSMNP1 share 86% identity and both proteins contain three casein kinase II and PKC (protein kinase C) phosphorylation sites, a putative N-glycosylation site and a PEST motif at the SLCterminus. HSMNP1 is a cytoplasmic protein and it specifically localizes to vesicles during the induction of apoptosis. In addition, HSMNP1 may be involved in normal as well as pathological myeloid development. Two isoforms of HSMNP1 exist due to alternative splicing events.

Function:
May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro).

Tissue Specificity:
Detected in brain.

Similarity:
Belongs to the dysbindin family.

SWISS:
Q9BQY9

Gene ID:
55861

Database links:

Entrez Gene: 55861 Human

Omim: 611453 Human

SwissProt: Q9BQY9 Human

Unigene: 655055 Human



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