May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD-E2 complexes which may provide a platform for interaction with CUL4A and WD repeat proteins.
Function:
May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD-E2 complexes which may provide a platform for interaction with CUL4A and WD repeat proteins.
Subunit:
Part of the DDD core complex containing DET1, DDA1 and DDB1. The DDD core complex recruits a specific UBE2E enzyme, such as UBE2E1, UBE2E2 UBE2E3, to form specific DDD-E2 complexes.
Similarity:
Belongs to the DDA1 family.
SWISS:
Q9BW61
Gene ID:
79016
Database links:
Entrez Gene: 79016 Human
Entrez Gene: 66498 Mouse
Entrez Gene: 688813 Rat
SwissProt: Q9BW61 Human
SwissProt: Q9D9Z5 Mouse
Unigene: 466154 Human
Unigene: 26072 Mouse
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