DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX59 is a 619 amino acid member of the DEAD box helicase protein family. Like many DEAD box helicase family members, DDX59 contains a Q motif, which controls ATP binding and hydrolysis. Expressed as two isoforms produced by alternative splicing, DDX59 contains one helicase SLCterminal domain and one HIT-type zinc finger.
Similarity:
Belongs to the DEAD box helicase family. DDX59 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase SLCterminal domain.
Contains 1 HIT-type zinc finger.
SWISS:
Q5T1V6
Gene ID:
83479
Database links:
Entrez Gene: 83479 Human
SwissProt: Q5T1V6 Human
Unigene: 497332 Human
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