Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. [provided by RefSeq, Jul 2008]
Function:
Has antibacterial activity.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed specifically in testis.
Similarity:
Belongs to the beta-defensin family.
SWISS:
Q9H1M3
Gene ID:
140881
Database links:
Entrez Gene: 140881 Human
Entrez Gene: 100068135 Horse
Entrez Gene: 100170137 Pig
SwissProt: Q9H1M3 Human
Unigene: 112087 Human
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