Home > Product > Antibody > Rabbit Anti-DEFB132 antibody
BD-32; beta 132; Beta-defensin 132; Beta-defensin 32; DB132_HUMAN; DEFB-32; DEFB132; Defensin; Defensin HEL-75; UNQ827.
Cat:
SL14257R
Species Reactivity:
(predicted: Human,)
Immunogen:
KLH conjugated synthetic peptide derived from human DEFB132:23-95/95
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
More
Unit:
Price: $
Product PDFs
Datasheet:


Beta-defensins are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. The family of Beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many Beta-defensins also are involved in sperm maturation and capacitation. Beta-defensin 32, also known as Beta-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.

Function:
Has antibacterial activity.

Subcellular Location:
Secreted.

Similarity:
Belongs to the beta-defensin family.

SWISS:
Q7Z7B7

Gene ID:
400830

Database links:

Entrez Gene: 400830 Human

SwissProt: Q7Z7B7 Human

Unigene: 516819 Human



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