Home > Product > Antibody > Rabbit Anti-DMRT1 antibody
DM domain expressed in testis 1; DM domain expressed in testis protein 1; DMRT 1; dmrt1; DMRT1_HUMAN; DMT 1; DMT1; Doublesex and mab 3 related transcription factor 1; Doublesex- and mab-3-related transcription factor 1.
Cat:
SL14346R
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human DMRT1:31-130/373
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
More
Unit:
Price: $
Product PDFs
Datasheet:


This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]

Function:
May be required for testis development.

Subcellular Location:
Nucleus.

Tissue Specificity:
Testis specific.

Similarity:
Belongs to the DMRT family.
Contains 1 DM DNA-binding domain.

SWISS:
Q9Y5R6

Gene ID:
1761

Database links:

Entrez Gene: 1761 Human

Omim: 602424 Human

SwissProt: Q9Y5R6 Human

Unigene: 98586 Human



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