Rabbit Anti-DPH4 antibody | Sunlong Medical

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1700030A21Rik; 2610027M02Rik; AV066965; AW240712; CSL type zinc finger containing protein 3; CSL-type zinc finger-containing protein 3; DJC24_HUMAN; DnaJ (Hsp40) homolog, subfamily C, member 24; DnaJ homolog subfamily C member 24; DNAJC24; DPH4

Cat:

SL14417R

Species Reactivity：

(predicted: Human,Mouse,Rat,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human DPH4:1-100/148

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]

Function:
Stimulates the ATPase activity of several Hsp70-type chaperones.

Subunit:
Monomer and homooligomer. Iron binding promotes oligomerization.

Subcellular Location:
Cytoplasm, cytoskeleton (By similarity).

Similarity:
Belongs to the DPH4 family.
Contains 1 DPH-type zinc finger.
Contains 1 J domain.

SWISS:
Q6P3W2

Gene ID:
120526

Database links:

Entrez Gene: 120526 Human

Entrez Gene: 99349 Mouse

Entrez Gene: 362184 Rat

Omim: 611072 Human

SwissProt: Q6P3W2 Human

SwissProt: Q91ZF0 Mouse

Unigene: 187269 Human

Unigene: 741895 Human

Unigene: 25661 Mouse

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