Home > Product > Antibody > Rabbit Anti-EBP2 antibody
EBNA1-binding protein 2; EBNA1 binding protein 2; ebna1bp2; EBP2; EBP2_HUMAN; NOBP; nuclear FGF3 binding protein; Nucleolar protein p40; P40; Probable rRNA processing protein EBP2; Probable rRNA-processing protein ebp2.
Cat:
SL14495R
Species Reactivity:
(predicted: Human,Mouse,Rat,)
Immunogen:
KLH conjugated synthetic peptide derived from human EBP2 :201-300/306
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


The replication and stable maintenance of latent Epstein-Barr virus DNA episomes in human cells requires only one viral protein, Epstein-Barr nuclear antigen 1 (EBNA1). EBNA1 binding protein 2, also designated p40/EBP2, is a nuclear protein required for the processing of the 27S pre-rRNA. EBP2 is highly conserved across species and is ubiquitously expressed in human tissues, especially myelogenous leukemia K-562. EBP2 specifically interacts with EBNA1, supporting the long-term maintenance of Epstein-Barr virus plasmids in human cells. The EBNA1-EBP2 complex is important for the stable segregation of Epstein-Barr virus episomes during cell division.

Function:
Required for the processing of the 27S pre-rRNA

Subcellular Location:
Nucleus > nucleolus.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the EBP2 family.

SWISS:
Q99848

Gene ID:
10969

Database links:

Entrez Gene: 10969 Human

Omim: 614443 Human

SwissProt: Q99848 Human

Unigene: 346868 Human



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