Home > Product > Antibody > Rabbit Anti-EBPL antibody
Delta8-delta7 sterol isomerase related protein; EBPL; EBPL_HUMAN; EBRP; Emopamil binding protein like; Emopamil binding related protein; Emopamil-binding protein-like.
Cat:
SL14496R
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human EBPL:51-150/206
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


EBPL is expressed as a homodimer with high levels found in liver, lung and kidney. As a transmembrane protein embedded on the endoplasmic reticulum, EBPL may function as a cholestenol delta-isomerase. The gene encoding EBPL is found on human chromosome 13. Comprising nearly 4% of the human genome, chromosome 13 contains around 114 million base pairs and encodes over 400 genes. Chromosome 13 houses key tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

Function:
Does not possess sterol isomerase activity and does not bind sigma ligands.

Subunit:
Homodimer.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.

Tissue Specificity:
Widely expressed with highest levels in liver, lung and kidney.

Similarity:
Belongs to the EBP family.

SWISS:
Q9BY08

Gene ID:
84650

Database links:

Entrez Gene: 84650 Human

SwissProt: Q9BY08 Human

Unigene: 433278 Human



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