Rabbit Anti-phospho-Ephrin B1 (Tyr317) antibody

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phospho-Ephrin B1 (phospho Y317); Ephrin B (phospho Y317); p-Ephrin B (phospho Y317); phospho-Ephrin B1 (Tyr317); phospho-Ephrin B2(Tyr316); CEK5 ligand; EFNB1; ELK L; EphrinB; Ephrin-B; ELK ligand; ELKL; EPH related receptor tyrosine kinase ligand 2; Eph

Cat:

SL10690R

Species Reactivity：

Human,(predicted: Mouse,Rat,Cow,Horse,)

Immunogen：

KLH conjugated Synthesised phosphopeptide derived from human Ephrin B1 around the phosphorylation site of Tyr317:PH(p-Y)EK

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $256.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.

Subunit:
Interacts with GRIP1 and GRIP2. Binds to Nipah virus G protein.

Tissue Specificity:
Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments.

Post-translational modifications:
Membrane; single pass type I membrane protein.

Similarity:
Belongs to the ephrin family.
Contains 1 ephrin RBD (ephrin receptor-binding) domain.

SWISS:
P52799

Gene ID:
1947

Database links:

Entrez Gene: 1947 Human

Entrez Gene: 13641 Mouse

Entrez Gene: 25186 Rat

Omim: 300035 Human

SwissProt: P98172 Human

SwissProt: P52795 Mouse

SwissProt: P52796 Rat

Unigene: 144700 Human

Unigene: 3374 Mouse

Unigene: 44398 Rat

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