Rabbit Anti-EPS8L1 antibody

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DRC 3; DRC3; Epidermal growth factor receptor kinase substrate 8 like protein 1; Epidermal growth factor receptor kinase substrate 8-like protein 1; Epidermal growth factor receptor pathway substrate 8 related protein 1; Epidermal growth factor recep

Cat:

SL14616R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Sheep,Guinea Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human EPS8L1:1-100/723

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.

Subunit:
Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Detected in placenta.

Similarity:
Belongs to the EPS8 family.
Contains 1 SH3 domain.

SWISS:
Q8TE68

Gene ID:
54869

Database links:

Entrez Gene: 54869 Human

Entrez Gene: 67425 Mouse

Entrez Gene: 361503 Rat

Omim: 614987 Human

SwissProt: Q8TE68 Human

SwissProt: Q8R5F8 Mouse

Unigene: 438862 Human

Unigene: 72392 Mouse

Unigene: 138370 Rat

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