ERGIC2, or PTX1, is a ubiquitously expressed nuclear protein that is downregulated in prostate carcinoma (Kwok et al., 2001 [PubMed 11445006]).[supplied by OMIM, Aug 2008]
Function:
Possible role in transport between endoplasmic reticulum and Golgi.
Subcellular Location:
Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus > cis-Golgi network membrane. Endoplasmic reticulum membrane. Cytoplasm. Nucleus. Cycles between the endoplasmic reticulum and the Golgi. PubMed:11445006 states that it localizes to the nucleus; PubMed:17196171 shows a partial localization in the nucleus.
Tissue Specificity:
Ubiquitously expressed.
Similarity:
Belongs to the ERGIC family.
SWISS:
Q96RQ1
Gene ID:
51290
Database links:
Entrez Gene: 51290 Human
Entrez Gene: 477657 Dog
Entrez Gene: 67456 Mouse
Entrez Gene: 393378 Zebrafish
Omim: 612236 Human
SwissProt: Q96RQ1 Human
SwissProt: Q9CR89 Mouse
SwissProt: Q7T2D4 Zebrafish
Unigene: 339453 Human
Unigene: 59812 Mouse
Unigene: 12056 Zebrafish
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