FAM188B2 is a 72 amino acid protein that is encoded by a gene which maps to human chromosome 3. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Similarity:
Belongs to the FAM188 family.
SWISS:
A8MYZ0
Gene ID:
646951
Database links:
Entrez Gene: 646951 Human
SwissProt: A8MYZ0 Human
Unigene: 669160 Human
|
|
