This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP 1alpha, a member of the CC chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells.
Subcellular Location:
Secreted.
Tissue Specificity:
Brain-specific.
Similarity:
Belongs to the FAM19/TAFA family.
SWISS:
Q7Z5A8
Gene ID:
284467
Database links:
Entrez Gene: 284467 Human
Entrez Gene: 329731 Mouse
Entrez Gene: 691123 Rat
SwissProt: Q7Z5A8 Human
SwissProt: Q7TPG6 Mouse
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