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Rabbit Anti-FAM49B antibody
Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The FAM49B gene product has been provisionally designated FAM49B pending further characterization.
Similarity:
Belongs to the FAM49 family.
SWISS:
Q9NUQ9
Gene ID:
51571
Database links:
Entrez Gene: 51571 Human
SwissProt: Q9NUQ9 Human
Unigene: 126941 Human
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