Rabbit Anti-FAM58A antibody

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Cyclin-M; Cyclin-related protein FAM58A; FA58A_HUMAN; Fam58a; Family with sequence similarity 58 member A; STAR.

Cat:

SL16006R

Species Reactivity：

(predicted: Human,Mouse,Rat,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human FAM58A:101-200/248

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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FAM58A (family with sequence similarity 58, member A) and FAM58B (family with sequence similarity 58, member B) are 248 amino acid and 252 amino acid proteins, respectively, that belong to the cyclin-like FAM58 subfamily. Existing as multiple alternatively spliced isoforms, FAM58A interacts with Sall1 and is thought to play a role in cellular proliferation. Defects in the gene encoding FAM58A are associated with toe syndactyly, telecanthus, and anogenital and renal malformations (STAR syndrome), which is characterized by renal and anogenital malformations. FAM58B, a protein that is related to FAM58A, is expressed in healthy retina and breast tissue, as well as in retinoblastoma and breast cancer cell lines, suggesting a role for FAM58B in tumor transformation and metastasis.

Function:
May have a role in cell proliferation.

DISEASE:
Toe syndactyly, telecanthus, and anogenital and renal malformations

Similarity:
Belongs to the cyclin family. Cyclin-like FAM58 subfamily.

SWISS:
Q8N1B3

Gene ID:
92002

Database links:

Entrez Gene: 92002 Human

Entrez Gene: 303321 Rat

Omim: 300708 Human

SwissProt: Q8N1B3 Human

SwissProt: Q4QQW5 Rat

Unigene: 496943 Human

Unigene: 38890 Rat

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