The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. The FAM9B gene product has been provisionally designated FAM9B pending further characterization.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed exclusively in testis.
Similarity:
Belongs to the FAM9 family.
SWISS:
Q8IZU0
Gene ID:
171483
Database links:
Entrez Gene: 171483 Human
Omim: 300478 Human
SwissProt: Q8IZU0 Human
Unigene: 371894 Human
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