Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis.
Function:
Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis.
Subunit:
May interact with FAS cytoplasmic domain (By similarity). Interacts with PARD3.
Subcellular Location:
Cytoplasm; cytoskeleton; centrosome; centriole. Cytoplasm; cytoskeleton; spindle pole. Cell junction. Note: Associates with the mother centriole. Localizes to the apical junction complex (AJC) in epithelial cells.
Tissue Specificity:
Present in various epithelial cells (at protein level).
SWISS:
Q8TES7
Gene ID:
85302
Database links:
Entrez Gene: 85302 Human
SwissProt: Q8TES7 Human
Unigene: 144068 Human
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