This gene encodes a member of the F-box protein family. This F-box protein interacts with S-phase kinase-associated protein 1A and cullin in order to form SCF complexes which function as ubiquitin ligases.[provided by RefSeq, Sep 2010]
Function:
This gene encodes a member of the F-box protein family. This F-box protein interacts with S-phase kinase-associated protein 1A and cullin in order to form SCF complexes which function as ubiquitin ligases.
Subunit:
Directly interacts with SKP1 and CUL1.
Subcellular Location:
Cytoplasm, myofibril, sarcomere, Z line.
Tissue Specificity:
Enriched in cardiac muscle.
Similarity:
Contains 1 F-box domain.
SWISS:
Q6P050
Gene ID:
283807
Database links:
Entrez Gene: 283807 Human
Entrez Gene: 74165 Mouse
Entrez Gene: 363083 Rat
Omim: 609088 Human
SwissProt: Q6P050 Human
SwissProt: Q8C7B6 Mouse
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