Rabbit Anti-FBXO22 antibody

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0610033L19Rik; 1600016C16Rik; F box only protein 22; F box protein 22; F box protein FBX22p44; F-box only protein 22; F-box protein FBX22p44; FBX22; FBX22_HUMAN; FBXO 22; FBXO22; FIST domain containing 1; FISTC1; FLJ13986; MGC124731; MGC317

Cat:

SL16047R

Species Reactivity：

Mouse,(predicted: Human,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human FBXO22:21-120/403

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Tissue Specificity:
Predominantly expressed in liver.

Similarity:
Contains 1 F-box domain.

SWISS:
Q8NEZ5

Gene ID:
26263

Database links:

Entrez Gene: 26263 Human

Entrez Gene: 71999 Mouse

Entrez Gene: 300724 Rat

Omim: 609096 Human

SwissProt: Q8NEZ5 Human

SwissProt: Q78JE5 Mouse

Unigene: 591115 Human

Unigene: 276429 Mouse

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