Rabbit Anti-FER1L5 antibody

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FR1L5_HUMAN; Fer1 like protein 5.

Cat:

SL16072R

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human FER1L5:1901-2093/2093

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

Function:
FER1L5 belongs to the ferlin family. There are three isoforms generated by alternative splicing.

Subunit:
Interacts (via second C2 domain) with EHD1 and EHD2 (By similarity).

Subcellular Location:
Cell Membrane; single pass membrane protein

Similarity:
Belongs to the ferlin family.
Contains 6 C2 domains.

SWISS:
A0AVI2

Gene ID:
90342

Database links:

Entrez Gene: 90342 Human

SwissProt: A0AVI2 Human

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