Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins.
Subcellular Location:
Nucleus.
Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.
SWISS:
Q96RJ6
Gene ID:
222894
Database links:
Entrez Gene: 222894 Human
SwissProt: Q96RJ6 Human
Unigene: 592168 Human
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