The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. A similar protein in mouse is located in the endoplasmic reticulum and binds calcium. [provided by RefSeq, Jul 2008]
Function:
FKBP7 belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. PPIases accelerate the folding of proteins during protein synthesis. FKBP7 contains two EF-hand domains and one PPIase FKBP-type domain. There are two named isoforms.
Subcellular Location:
Endoplasmic reticulum lumen.
Post-translational modifications:
Glycosylated (By similarity).
Similarity:
Contains 2 EF-hand domains.
Contains 1 PPIase FKBP-type domain.
SWISS:
Q9Y136
Gene ID:
51661
Database links:
Entrez Gene: 51661 Human
Entrez Gene: 14231 Mouse
Entrez Gene: 295672 Rat
Omim: 607062 Human
SwissProt: Q9Y136 Human
SwissProt: O54998 Mouse
|
|
