Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc?receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. The MPV17L2 gene product has been provisionally designated MPV17L2 pending further characterization.
Function:
FKSG24 is a potential multi-pass membrane protein. It belongs to the peroxisomal membrane protein PXMP2/4 family. The exact function of FKSG24 remains unknown.
Subcellular Location:
Membrane; Multi-pass membrane protein (potential)
Similarity:
Belongs to the peroxisomal membrane protein PXMP2/4 family.
SWISS:
Q567V2
Gene ID:
84769
Database links:
Entrez Gene: 84769 Human
Entrez Gene: 234384 Mouse
SwissProt: Q567V2 Human
SwissProt: Q8VIK2 Mouse
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