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Rabbit Anti-TRMT2B antibody
This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Nov 2009]
Function:
Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation.
Similarity:
Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family.
SWISS:
Q96GJ1
Gene ID:
79979
Database links:
Entrez Gene: 79979 Human
GenBank: NM_024917 Human
SwissProt: Q96GJ1 Human
Unigene: 496501 Human
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