Home > Product > Antibody > Rabbit Anti-GAGE1 antibody
Cancer/testis antigen 4.1; GAGE-1; Antigen MZ2-F; CT4.1; CT4 1; GAGE1_HUMAN; G antigen 1; GAGE 1; MZ2 F antigen.
Cat:
SL16207R
Species Reactivity:
(predicted: Human,)
Immunogen:
KLH conjugated synthetic peptide derived from human GAGE1:51-139/139
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Function:
Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes. Completely silent in normal adult tissues, except testis.

Tissue Specificity:
Expressed in a variety of tumor tissues but not in normal tissues, except testis.

Similarity:
Belongs to the GAGE family.

SWISS:
Q13065

Gene ID:
2543

Database links:

Entrez Gene: 2543 Human

Omim: 300594 Human

SwissProt: Q13065 Human

Unigene: 632815 Human



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