GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002 [PubMed 12042312]).[supplied by OMIM, Mar 2008]
Function:
Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5'-GACCACCCASLC3'.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the GLI C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.
SWISS:
Q8NSF1
Gene ID:
148979
Database links:
Entrez Gene: 148979 Human
Entrez Gene: 230587 Mouse
Omim: 610378 Human
SwissProt: Q8NSF1 Human
SwissProt: Q8K1M4 Mouse
Unigene: 306691 Human
Unigene: 331757 Mouse
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