The Golgi complex plays an essential role in the post-translational modification and sorting of proteins transported from the endoplasmic reticulum (ER). The Golgi stack consists of a distinct cis face, or entry face, and a trans face, or exit face, which are connected via the cis, medial and trans Golgi networks. GOLGA8H (putative golgin subfamily A member 8I) is a 632 amino acid protein that belongs to the GOLGA8 family. Localizing to Golgi apparatus, GOLGA8H may play a role in Golgi structure maintenance. The gene encoding GOLGA8H maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
Subcellular Location:
Golgi Apparatus
Similarity:
Belongs to the GOLGA8 family.
SWISS:
P0CJ92
Gene ID:
728498
Database links:
Entrez Gene: 728498 Human
SwissProt: P0CJ92 Human
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