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Rabbit Anti-GPCR GPR8 antibody
The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor. The encoded protein is similar in sequence to another G protein-coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain. [provided by RefSeq, Jul 2008]
Function:
This protein interacts specifically with a number of opioid ligands and is a receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals.
Subcellular Location:
Cell Membrane
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
P48146
Gene ID:
2832
Database links:
Entrez Gene: 2832 Human
Omim: 600731 Human
SwissProt: P48146 Human
Unigene: 248118 Human
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