GPR123 (G protein-coupled receptor 123) is a 1,279 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Existing as two alternatively spliced isoforms, GPR123 functions as an orphan receptor that is expressed in adult and fetal brain, and in adult spinal cord. The gene encoding GPR123 maps to human chromosome 10q26.3 and mouse chromosome 7 F4.
Function:
Orphan receptor.
Subcellular Location:
Cell membrane.
Similarity:
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
SWISS:
Q86SQ6
Gene ID:
84435
Database links:
Entrez Gene: 84435 Human
Entrez Gene: 100727635 Guinea pig
Entrez Gene: 100050642 Horse
Entrez Gene: 10062388 Pig
Omim: 612302 Human
SwissProt: Q86SQ6 Human
Unigene: 491412 Dog
Unigene: 435183 Human
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