Rabbit Anti-GPRASP1 antibody

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G-protein coupled receptor-associated sorting protein 1; GASP; GASP-1; GASP1; GASP1_HUMAN; Gprasp1; KIAA0443.

Cat:

SL16299R

Species Reactivity：

(predicted: Human,Mouse,Rat,Cow,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human GPRASP1:1001-1100/1395

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]

Function:
May modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra.

Similarity:
Belongs to the GPRASP family.

SWISS:
Q5JY77

Gene ID:
9737

Database links:

Entrez Gene: 9737 Human

Omim: 300417 Human

SwissProt: Q5JY77 Human

Unigene: 522729 Human

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