Rabbit Anti-GRAMD4 antibody

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Death-inducing protein; GRAM domain-containing protein 4; GRAM4_HUMAN; GRAMD4.

Cat:

SL16309R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human GRAMD4:1-100/578

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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GRAMD4 is a mitochondrial effector of E2F1 (MIM 189971)-induced apoptosis (Stanelle et al., 2005 [PubMed 15565177]).[supplied by OMIM, Jan 2011]

Function:
Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53.

Subcellular Location:
Mitochondrion membrane. Colocalizes with COX4I1.

Tissue Specificity:
Expressed in lung and in primary lung squamous cell carcinoma (LSCC).

Similarity:
Contains 1 GRAM domain.

SWISS:
Q6IC98

Gene ID:
23151

Database links:

Entrez Gene: 23151 Human

Omim: 613691 Human

SwissProt: Q6IC98 Human

Unigene: 475150 Human

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