Rabbit Anti-GTPBP4 antibody

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Chronic renal failure gene protein; CRFG; G protein binding protein CRFG; GTP binding protein 4; GTP-binding protein NGB; Gtpbp4; NGB; NOG1; NOG1_HUMAN; Nucleolar GTP binding protein 1; Nucleolar GTP-binding protein 1.

Cat:

SL16368R

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human GTPBP4:21-120/634

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008]

Function:
Involved in the biogenesis of the 60S ribosomal subunit.

Subcellular Location:
Nucleus； nucleolus.

Similarity:
Belongs to the GTP1/OBG family. NOG subfamily.

SWISS:
Q9BZE4

Gene ID:
23560

Database links:

Entrez Gene: 23560 Human

Entrez Gene: 69237 Mouse

Entrez Gene: 114300 Rat

SwissProt: Q9BZE4 Human

SwissProt: Q99ME9 Mouse

SwissProt: Q99P77 Rat

Unigene: 215766 Human

Unigene: 4360 Mouse

Unigene: 96111 Rat

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