Rabbit Anti-ZSCAN4 antibody

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FLJ35105; MGC126787; MGC126789; Zinc finger and SCAN domain containing 4; Zinc finger and SCAN domain containing protein 4; Zinc finger and SCAN domain-containing protein 4; Zinc finger protein 494; ZNF 494; ZNF494; ZSCA4_HUMAN; ZSCAN4.

Cat:

SL16399R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human ZSCAN4:331-433/433

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 2037270]).[supplied by OMIM, May 2010]

Function:
Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells.

Subcellular Location:
Nucleus. Chromosome > telomere.

Similarity:
Contains 4 C2H2-type zinc fingers.
Contains 1 SCAN box domain.

SWISS:
Q8NAM6

Gene ID:
201516

Database links:

Entrez Gene: 201516 Human

Omim: 613419 Human

SwissProt: Q8NAM6 Human

Unigene: 469663 Human

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