Rabbit Anti-HSD17B7 antibody

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17 beta HSD 7; 17 beta hydroxysteroid dehydrogenase 7; 17 beta hydroxysteroid dehydrogenase type VII; 17-beta-HSD 7; 17-beta-hydroxysteroid dehydrogenase 7; 17beta hydroxysteroid dehydrogenase; 3 keto steroid reductase; 3-keto-steroid reductase; D

Cat:

SL16528R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human HSD17B7:31-130/341

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 1285965]).[supplied by OMIM, May 2010]

Function:
Responsible for the reduction of the keto group on the SLC3 of sterols.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. Isoform 3 is expressed in eye ciliary epithelial cells and neuroendocrine cells.

Post-translational modifications:
Phosphorylated.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

SWISS:
P56937

Gene ID:
51478

Database links:

Entrez Gene: 51478 Human

Entrez Gene: 15490 Mouse

Entrez Gene: 29540 Rat

Omim: 606756 Human

SwissProt: P56937 Human

SwissProt: O88736 Mouse

SwissProt: Q62904 Rat

Unigene: 492925 Human

Unigene: 12882 Mouse

Unigene: 7040 Rat

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