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Rabbit Anti-TRAF3IP3 antibody
The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Function:
This protein may function as an adapter molecule that regulates TRAF3-mediated JNK activation.
Subunit:
Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain (By similarity).
Subcellular Location:
Membrane; single pass type IV membrane protein
SWISS:
Q9Y228
Gene ID:
80342
Database links:
Entrez Gene: 80342 Human
SwissProt: Q9Y228 Human
SwissProt: Q8C0G2 Mouse
Unigene: 147434 Human
Unigene: 261259 Mouse
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