Rabbit Anti-TRAPPC11 antibody

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C4orf41; FLJ12716; Foie gras homolog; TPC11_HUMAN; foigr; gry; Gryzun homolog; Trafficking protein particle complex 11; Trafficking protein particle complex subunit 11.

Cat:

SL16581R

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Pig,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human TRAPPC11:151-250/1133

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

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Other Information
Citations
Protein Attributes
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The protein encoded by this gene is a subunit of the TRAPP (transport protein particle) tethering complex, which functions in intracellular vesicle trafficking. This subunit is involved in early stage endoplasmic reticulum-to-Golgi vesicle transport. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Function:
Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.

Subunit:
Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12.

Subcellular Location:
Golgi apparatus; cis-Golgi network

DISEASE:
Limb-girdle muscular dystrophy 2S (LGMD2S) [MIM:615356]: A form of limb-girdle muscular dystrophy characterized by proximal muscle weakness with childhood onset, resulting in gait abnormalities and scapular winging. Serum creatine kinase is increased. A subset of patients may show a hyperkinetic movement disorder with chorea, ataxia, or dystonia and global developmental delay. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the TRAPPC11 family.

SWISS:
Q7Z392

Gene ID:
60684

Database links:

Entrez Gene: 60684 Human

Entrez Gene: 64714 Mouse

Entrez Gene: 290746 Rat

Omim: 614138 Human

SwissProt: Q7Z392 Human

SwissProt: B2RXC1 Mouse

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