Rabbit Anti-TRAPPC4 antibody

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CGI 104; Hematopoietic stem/progenitor cell protein 172; HSPC172; PTD009; SBDN; TPPC4_HUMAN; Synbindin; Trafficking protein particle complex subunit 4; TRAPPC4; TRS23; TRS23 homolog.

Cat:

SL16585R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human TRAPPC4:101-200/219

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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TRAPPC4 is a postsynaptic protein belonging to the TRAPPC4 subfamily of the TRAPP small subunits family of proteins. Expressed in neurons and localizing to the Golgi apparatus, TRAPPC4 is believed to be involved in vesicular transport from the endoplasmic reticulum (ER) to the Golgi, functioning as a component of the multisubunit transport protein particle (TRAPP) complex. Similar to other proteins involved in vesicular transport or synaptic function, TRAPPC4 contains a nonclassical PDZ domain, a TRAPPC1-like domain and a SLCterminus that is similar to a short segment of RyR. Via its nonclassical PDZ domain, TRAPPC4 binds to the SLCterminal EFYA motif of Syndecan-2, suggesting that TRAPPC4 may play an important role in dendritic spine morphogenesis through membrane-trafficking.

Function:
TRAPPC4 is part of the multisubunit TRAPP (transport protein particle) complex and interacts with SDC2. It may play a role in vesicular transport from endoplasmic reticulum to Golgi. TRAPP proteins are involved in tethering during vesicle transport.

Subunit:
Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12. Interacts with SDC2 (By similarity).

Subcellular Location:
Endoplasmic reticulum and Golgi Apparatus

Similarity:
Golgi apparatus, cis-Golgi network (By similarity). Endoplasmic reticulum (By similarity).
Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.

SWISS:
Q9Y296

Gene ID:
51399

Database links:

Entrez Gene: 51399 Human

Entrez Gene: 60409 Mouse

Entrez Gene: 367073 Rat

Omim: 610971 Human

SwissProt: Q9Y296 Human

SwissProt: Q9ES56 Mouse

SwissProt: Q69BT7 Rat

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